AGRO-WASTE AS SOURCE OF FINE AND INDUSTRIAL CHEMICALS: SYNTHESIS OF 2-FORMYL-6-HYDROXYBENZOIC ACID AND 4-METHOXYISOBENZOFURAN-1,3-DIONE FROM CASHEW NUT SHELL LIQUID

Lydia Kisula, Tanzania Industrial Research Developments Organization, P.O. Box 23235 Dar es Salaam, TanzaniaFollow
Stephen J.M. MdachiFollow
Charles de Koning, School of Chemistry, University of Witwatersrand, Private Bag 3, Wits, 2050, Republic of South AfricaFollow
Quintino A. Mgani, Chemistry Department, University of Dar es Salaam, P.O. Box 35061, Dar es Salaam, TanzaniaFollow

Section

Physical Sciences

Abstract

This paper reports on the synthesis of 2-formyl-6-hydroxybenzoic acid (8) and 4-methoxyisobenzofuran-1,3-dione (10) from a renewable natural material Cashew Nut Shell Liquid (CNSL) achieved in five and seven steps, respectively. Anacardic acid was isolated from CNSL, dimethoxylated into (E)-methyl 2-methoxy-6-(pentadec-8-enyl)benzoate which was subsequently hydrogenated into methyl 2-methoxy-6-pentadecylbenzoate. Benzylic bromination of the methoxyester, and dehydrobromination afforded (E)-methyl 2-methoxy-6-(pentadec-1-enyl)benzoate which upon ozonolysis gave methyl 2-formyl-6-methoxybenzoate. Oxidation and dehydration of 8 formed methoxyphthalic anhydride (10). The work reported in this paper has further demonstrated the resourcefulness of cashew nut shell liquid as a renewable natural resource for synthesis of fine and industrial chemicals.

Recommended Citation

Kisula, Lydia; Mdachi, Stephen J.M.; Koning, Charles de; and Mgani, Quintino A. (2015) "AGRO-WASTE AS SOURCE OF FINE AND INDUSTRIAL CHEMICALS: SYNTHESIS OF 2-FORMYL-6-HYDROXYBENZOIC ACID AND 4-METHOXYISOBENZOFURAN-1,3-DIONE FROM CASHEW NUT SHELL LIQUID," Tanzania Journal of Science: Vol. 41: Iss. 1, Article 10.
Available at:https://doi.org/10.65085/2507-7961.1814